dear seeker of knowledge, my former university has decided to remove access to the server running my software and downloads … We are working on setting up new servers. I am sorry for the inconvenience. Several tools can be accessed from the links below. If you use our software programs or databases, then please cite our work. It is fair and polite, and it helps me maintain a lab to provide even more tools.

Best wishes, Frans Mulder

You can find POTENCI python source code for random coil chemical shift prediction at github: https://github.com/protein-nmr/POTENCI

You can download the CheZOD database used for testing disorder predictors at this link: http://www.protein-nmr.org/CheZOD.tar.gz

The ncSPC program for assessing structural propensities is found here (for the moment): http://linuxnmr02.chem.rug.nl/ncSPC


Sequence-specific random coil chemical shifts of intrinsically disordered proteins.
Tamiola K, Acar B, Mulder FAA.
J Am Chem Soc. 2010 Dec 29;132(51):18000-3. doi: 10.1021/ja105656t

Using NMR chemical shifts to calculate the propensity for structural order and disorder in proteins.
Tamiola K, Mulder FAA.
Biochem Soc Trans. 2012 Oct;40(5):1014-20

There is Diversity in Disorder-"In all Chaos there is a Cosmos, in all Disorder a Secret Order".
Nielsen JT, Mulder FAA.
Front Mol Biosci. 2016 Feb 11;3:4. doi: 10.3389/fmolb.2016.00004

POTENCI: prediction of temperature, neighbor and pH-corrected chemical shifts for intrinsically disordered proteins.
Nielsen JT, Mulder FAA.
J Biomol NMR. 2018 Mar;70(3):141-165. doi: 10.1007/s10858-018-0166-5

Quality and bias of protein disorder predictors.
Nielsen JT, Mulder FAA.
Sci Rep. 2019 Mar 26;9(1):5137. doi: 10.1038/s41598-019-41644-w